Gynaecomastia or Breast Tissue
Because of the testicular failure, the testicles may be stimulated to make more oestrogen than that seen in an XY male. This may give rise to an increase in breast tissue or gynaecomastia. This can sometimes be exacerbated by testosterone replacement therapy (TRT) as testosterone can often also be transformed into oestrogen.
Although there is an increased risk of breast cancer, it appears to be about 70% lower than for females. XY/XXY mosaics may have a slightly higher risk than non-mosaics.
It is recommended that all KS adults should self-examine regularly.
Where there is excessive breast tissue which is causing distress, it may be funded by the NHS. However, this will depends on individual consultants, the area of the country and the individual’s overall health.
A plastic surgeon with previous experience should be used rather than a general surgeon.
In some situations a small incision can be made just beneath the breast and the excess tissue removed by liposuction. This can be carried out as a day procedure. However this may not always be suitable.
If liposuction is not possible, then a small incision is made just below the nipple and the excess tissue is removed. This will leave a small scar which should be unobtrusive.
This should be discussed with your surgeon so that you know what to expect.
As long as the surgeon is careful to remove all breast tissue, there should not be any re-growth of breast tissue at a later stage. However, it is important that any treatment with testosterone is then carefully monitored, to avoid excess levels which could again be transformed to oestrogen.